The only game I'm really looking forward to is RE5. I haven't kept up with games at all the past few months, but I still like the RE games. I liked 4 a lot, but I hope 5 isn't so much action.
Assassin's Creed looks cool too. I'm glad it's coming out for 360, since that's all I have.
MGS4 looks cool, but I don't have a PS3. Plus, I kinda get into the MGS games but I start to lose interest fast. Though that happens with A LOT of games I play, I still haven't gone back to MGS3 since it came out.
Call of Duty 4. Maybe. I'm not a huge fan of FPS, but I have fun from time to time.
Army of Two - I'm gonna keep my eye on this one.